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Healing Critical Defects in the Femur

Posted on December 13, 2012 by Arun Shanbhag

Christopher Evans, PhD, is the Maurice Mueller Professor of Orthopaedic Surgery and Director of the Center for Advanced Orthopaedic Studies in the Department of Orthopaedic Surgery at Beth Israel Deaconess Medical Center.

Vaida Glatt, PhD, is a Senior Research Fellow with the Trauma Research Group of the Institute of Health and Biomedical Innovation at Queensland University of Technology Brisbane, Queensland.

Introduction
Large segmental defects heal poorly and often present clinical challenges. Approaches used to improve healing include autograft and allograft bone, distraction osteogenesis, vascularized bone grafts and the application of BMP-2 and BMP-7. We wanted to determine whether modulation of the mechanical environment could improve bone healing in a rat femoral segmental defect model. (more…)

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Recovering From Injury

Posted on March 15, 2012 by Arun Shanbhag

David RingDavid Ring, MD, PhD is an Orthopaedic Hand Surgeon at the Massachusetts General Hospital, Boston, specializing in arm fractures, post-traumatic reconstruction, hand surgery and elbow surgery.

Some fractures frustrate us. Adverse events always affect us. But nothing takes the wind from our sails more than a patient who has greater pain and disability than expected. We are used to having answers and knowing what to do. For diagnoses like open fracture, compartment syndrome, or an elbow that will not stay reduced, we feel like we can make a difference. But when our patients have stiff fingers, a stiff elbow, or persistent disabling pain the answers do not always come easily (1). (more…)

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Matt Jimenez: Somatic Cells for Nonunions

Posted on March 9, 2011 by Arun Shanbhag

Matt Jimenez MGH Grand Rounds Somatic Cells for NonunionsSomatic Cells for Nonunions
Matt Jimenez, MD
University of Illinois at Chicago,
Department of Orthopaedic Surgery
Lutheran General Hospital, Chicago, IL
Grand Rounds presented on Jan 20, 2011 at the O’Keefe Auditorium, Massachusetts General Hospital, Boston, MA

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