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Healing Critical Defects in the Femur

Christopher Evans, PhD, is the Maurice Mueller Professor of Orthopaedic Surgery and Director of the Center for Advanced Orthopaedic Studies in the Department of Orthopaedic Surgery at Beth Israel Deaconess Medical Center.

Vaida Glatt, PhD, is a Senior Research Fellow with the Trauma Research Group of the Institute of Health and Biomedical Innovation at Queensland University of Technology Brisbane, Queensland.


Introduction
Large segmental defects heal poorly and often present clinical challenges. Approaches used to improve healing include autograft and allograft bone, distraction osteogenesis, vascularized bone grafts and the application of BMP-2 and BMP-7. We wanted to determine whether modulation of the mechanical environment could improve bone healing in a rat femoral segmental defect model. (more…)

Recovering From Injury

David RingDavid Ring, MD, PhD is an Orthopaedic Hand Surgeon at the Massachusetts General Hospital, Boston, specializing in arm fractures, post-traumatic reconstruction, hand surgery and elbow surgery.


Some fractures frustrate us. Adverse events always affect us. But nothing takes the wind from our sails more than a patient who has greater pain and disability than expected. We are used to having answers and knowing what to do. For diagnoses like open fracture, compartment syndrome, or an elbow that will not stay reduced, we feel like we can make a difference. But when our patients have stiff fingers, a stiff elbow, or persistent disabling pain the answers do not always come easily (1). (more…)

Pediatric Supracondylar Fractures

Samantha SpencerSamantha Spencer, MD is a pediatric orthopaedist at Children’s Hospital, Boston, specializing in trauma, lower extremity, vascular anomalies, osteogenesis imperfecta and skeletal dysplasias.


Pediatric supracondylar fractures are the most common elbow fractures in children. Approximately 7-10% of supracondylar fractures and up to 50% of severely displaced Type III supracondylar fractures present with a neurologic injury: radial nerve (41.2%); median nerve (36%); ulnar nerve (22.8%). Vascular injury is seen in 1% of displaced supracondylar fractures. Nondisplaced fractures/minimally displaced Type II fractures can be safely managed with 3 weeks of immobilization. The standard of care for displaced fractures is reduction/pin fixation for 3-4 weeks, then early mobilization.

Problematic Fractures: Tips for Identification
The majority (90-95%) of displaced supracondylar fractures can be managed with closed reduction and pinning with excellent outcomes. However, a subset of fractures need open reduction and are at risk for neurovascular sequelae. A problematic fracture should be suspected whenever there is less than a fully intact neurovascular exam or severe fracture displacement.

An adequate neurovascular exam can be difficult in a child but should always be documented, or – should an adequate exam not be possible – whatever can be obtained should be documented. Capillary refill should be immediate; sluggish refill should raise concern for vascular injury or entrapment. Similarly, nerve deficits or paresthesias signify nerve stretch or entrapment. These fractures need urgent treatment.
Radiographically, the direction of the proximal metaphyseal spike predicts the likely neurovascular injury: anterior (direct posterior extension type)-median nerve/brachial artery, medial (posterolateral extension type or flexion type)-ulnar nerve, lateral (posteromedial extension type)-radial nerve. Figure 1 shows a severely displaced extension type which had entrapped median nerve and brachial artery.

Figure 1: Elbow x-ray demonstrating severely displaced supracondylar fracture.
Trauma Rounds Pediatric Supracondylar Fractures, Samantha Spencer Childrens Hospital Boston

How to Open Reduce & Fix Pediatric Supracondylar Fractures
Once a fracture has been identified as possibly problematic and has unsatisfactory closed reduction, it is important to have appropriate setup with a hand table, sterile tourniquet, C-arm and hand instrument set. A vascular surgeon should be available if needed.

When opening pediatric fractures, it is best to always open over the tear in the periosteum. For supracondylar fractures, a 3-5 cm anterior incision in the elbow crease usually allows easy exposure of the fracture and the neurovascular structures. These are often tented over the proximal fracture fragment. Once any entrapped muscle and/or nerves/vessels are cleared, the fracture can be open reduced and pinned in the usual fashion. The nerves and vessels can then be assessed with the tourniquet down. It often takes warming and dripping vasodilative agents on the brachial artery for 10-15 minutes to relieve vasospasm. If pulsatile flow returns – which is common – standard closure and bivalved casting can proceed. If flow does not return or an arterial injury is visible, a vascular surgery assessment for need of brachial artery repair must occur.

After either closed or open reduction and pinning of a supracondylar fracture (Figure 2), children should be comfortable with little narcotic requirement and no negative change to their preoperative neurologic exam. Significant pain and increasing pain medicine requirements are the best indicators in children of evolving compartment syndrome or missed arterial injury or entrapped nerve. Entrapment should particularly be suspected if pain increases and nerve function is decreased after closed reduction and pinning. These issues require emergent surgical exploration.

Figure 2: Postoperative AP and Lateral x-rays of pin configurations.
Trauma Rounds Pediatric Supracondylar Fractures, Samantha Spencer Childrens Hospital Boston

Trauma Rounds Pediatric Supracondylar Fractures, Samantha Spencer Childrens Hospital Boston

Conclusions
The majority of displaced supracondylar fractures can be managed with closed reduction and pin fixation in a regularly scheduled OR time. However, displaced fractures with preoperative neurovascular deficits should raise concern for neurovascular entrapment and injury. Indications for open reduction of closed pediatric supracondylar fractures include inadequate hand perfusion after pinning, inability to obtain an adequate reduction, and evidence of iatrogenic neurovascular injury postoperatively. When open reduction is performed, an anterior antecubital crease incision affords access to the torn periosteum as well as the neurovascular structures.

Bibliography
1. White L, Mehlman CT, Crawford AH. Perfused, pulseless, and puzzling: a systematic review of vascular injuries in pediatric supracondylar humerus fractures and results of a POSNA questionnaire: J Pediatr Orthop 2010; 30(4):328-35.
2. Campbell CC, et al, Neurovascular injury and displacement in type III supracondylar humerus fractures: J Pediatr Orthop 1995; 15(1):47-52.
3. Kasser JR and Beaty JH, Supracondylar Fractures of the Distal Humerus: Chap 14 In Rockwood and Wilkins, Fractures in Children, 6th ed. Lippincott Williams & Wilkins; Philadelphia, PA. 2006: 543-589.

Fractures of the Distal Humerus

Jesse JupiterJesse Jupiter, MD is a Hand & Upper Extremity Orthopaedic Surgeon, at the Massachusetts General Hospital.


Fractures of the distal end of the humerus, while relatively uncommon, continue to stimulate discussion as to the optimal method of treatment. Unfortunately, there are relatively few Level I or even Level II studies to guide the fracture surgeon.1 I will attempt to identify and clarify a number of contemporary issues and provide a perspective of 30 years experience in the study and management of these injuries.
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THA for Femoral Neck Fractures

Michael Weaver, MD is an Orthopaedic Trauma Surgeon, at Brigham & Women’s Hospital.


The reduction and fixation of displaced femoral neck fractures has an unacceptably high rate of failure, particularly in the geriatric population. Reconstruction with either hemiarthroplasty or total hip arthroplasty (THA) is the accepted treatment for these fractures. In active patients reconstruction with a total hip has advantages in terms of pain relief, functional outcome, and prosthesis longevity (1).

While many surgeons are skilled in performing THA for degenerative conditions of the hip – including osteoarthritis and avascular necrosis – patients with femoral neck fractures present several unique challenges. Here are my experiences:

Intraoperative Fracture
Femoral neck fractures are fragility fractures associated with poor bone quality, a marker of osteoporosis. The trend in arthroplasty has been toward press-fit femoral components that allow for bone ingrowth and long-term stability. Thus, I use ingrowth femoral stems with a more canal-filling geometry instead of taper-type stems to reduce hoop stresses and prevent fracture. A doubled up 16-gauge circlage wire should be placed prophylactically between the greater and lesser trochanters prior to broaching.
Care must also be taken with placement and impacting of the acetabular component. There is usually no subchondral sclerosis, and it can be easy to breach the medial wall with the acetabular reamers. Supplementing acetabular fixation with at least 2 screws can prove useful.

Pre-operative pelvic AP is the template to guide radiographic placement of the cup. Adjust the C-arm orientation to recreate this image.
Trauma Rounds THA for Femoral Neck Fractures, Michael Weaver
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Intra-articular Distal Radius Fractures

Brandon Earp, MD, is an Hand & Upper Extremity Surgeon, at Brigham & Women’s Hospital and Instructor of Orthopaedic Surgery at Harvard Medical School.


Your patient comes in after a mechanical fall onto an outstretched hand. A significant deformity of the wrist and edema are noted clinically and the patient’s discomfort is obvious. Radiographs demonstrate a displaced, dorsally angulated distal radius fracture with loss of radial height, radial translation, and intra-articular involvement. You see the patient, perform an appropriate clinical workup, reduce and splint the fracture.


Post-injury PA view of the wrist demonstrates a displaced comminuted intra-articular distal fracture. CT scan was later obtained to better understand the fracture pattern for surgical planning. 
Trauma Rounds Intra-articular distal radius Fractures, Brandon Earp
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Matt Jimenez: Somatic Cells for Nonunions

Matt Jimenez MGH Grand Rounds Somatic Cells for NonunionsSomatic Cells for Nonunions
Matt Jimenez, MD
University of Illinois at Chicago,
Department of Orthopaedic Surgery
Lutheran General Hospital, Chicago, IL
Grand Rounds presented on Jan 20, 2011 at the O’Keefe Auditorium, Massachusetts General Hospital, Boston, MA


Femur Fractures Around Hip Implants

David Lhowe, MD, is an Orthopedic Trauma Surgeon, at Massachusetts General Hospital and Assistant Clinical Professor of Orthopaedic Surgery at Harvard Medical School.


Approximately 200,000 total hip replacements and an equal number of hemiarthroplasties are performed annually in the United States. With the marked success of this procedure, patients are able to maintain active lifestyles for many more years. Consequently, millions of elderly are at risk for fracture around their prosthesis.

Periprosthetic fractures typically result from common household falls. The Mayo Clinic reported a 1% prevalence of periprosthetic fracture after primary THR, increasing to 4% following revision surgery (1). Barring dramatic improvements in treating osteoporosis or reducing falls in an aging population, periprosthetic fractures will become an increasing medical and societal burden.

Fortunately, the majority of periprosthetic fractures do not result in implant loosening and may be managed without the need for implant revision. These fractures include the isolated trochanteric fractures (Vancouver A), diaphyseal fractures about a well-fixed stem (Vancouver B1), and fractures well below the distal tip of the stem (Vancouver C). Complex management with revision of components is required when the femoral stem is loose (Vancouver B2) and loosening is further complicated by inadequate bone stock (Vancouver B3). These variants are appropriately referred to experienced hip revision surgeons.

Femur fracture around well-fixed total hip replacement
Femur fracture around a well-fixed cemented THR component. Note the presence of a medullary cement plug in the distal fragment.
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Evaluating the Cervical Spine

Mitch Harris, MD, is Chief of the Orthopedic Trauma Service, at Brigham and Women’s Hospital, and Associate Professor of Orthopaedic Surgery at Harvard Medical School.
Here, Dr Harris shares a very useful algorithm for evaluating patients with trauma to the cervical spine.


Imagine getting called to the Emergency Department to evaluate a painful and swollen knee after a skiing accident. The plain x-rays are read as normal, with no evidence of acute fracture and demonstrate evidence of degenerative arthritis of the knee. If the patient is experiencing too much pain to allow for an adequate exam, a knee brace will be provided and the patient re-evaluated in the office in 7-10 days. If there is significant ligamentous injury, the brace will suffice for temporary stability and a follow-up MRI might be required to fully define the extent of the injury.

Now consider another presentation. This time the mechanism of injury is a fall from standing in an elderly woman and the area of concern is her cervical spine. The patient has a black eye, no history of loss of consciousness and complains of neck pain while in the collar. There are no other associated injuries. Plain x-rays of her cervical spine are read as normal, with no evidence of acute fracture and demonstrate evidence of degenerative arthritis of the neck. The questions now are: what should the next tests be, and can the patient be safely discharged in a collar for a follow-up appointment in 1-2 weeks?

Normal appearing Left and Right facets of the cervical spine from MD Computerized Tomography (MDCT) scan.
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Delivering Allograft Bone Chips

George Dyer, MD, is an Orthopaedic Surgeon at Brigham and Women’s Hospital, and Instructor of Orthopaedic Surgery at Harvard Medical School. Here, Dr Dyer shares a useful trick for simplifying the delivery of allograft bone chips to a small graft site.


The conventional method of delivering bone chips into an area to be grafted typically involves plucking them out of a little bowl with forceps and trying to place them into the recipient site without spilling them everywhere. This often results in a mess: graft falls out of the forceps while en route to the surgical site, landing in soft tissues, on the drapes, or on the floor. Graft and time are wasted. This process is especially awkward when the recipient site is a small hole or window and the surgeon is attempting to pack the graft into it.
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